Dr Lesley Cheng from the Hill lab recently gave a TEDx talk on Dementia and her work developing a blood based test for Alzheimer’s Disease. https://www.youtube.com/watch?v=R9OUz3sHzZk
Congrats to Ben Scicluna who was awarded one of three ‘Featured Abstract’ presentations at the ISEV 2016 Conference in Rotterdam!
Our first whole-transcriptome analysis of gene expression changes is in press: Cheng L, Quek CYJ, Hung LW, Sharples RA, Sherratt NA, Barnham KJ, Hill AF. Gene dysregulation is restored in the Parkinson’s disease MPTP neurotoxic mice model upon treatment of the therapeutic drug CuII(atsm). Scientific Reports | 6:22398 | DOI: 10.1038/srep22398 1
New review in IJMS – part of a special issue on EVs: Vella LJ, Hill AF*, Cheng L. Focus on Extracellular Vesicles: Exosomes and Their Role in Protein Trafficking and Biomarker Potential in Alzheimer’s and Parkinson’s Disease. International Journal of Molecular Sciences. 2016, 17(2), 173; doi:10.3390/ijms17020173
New paper from the lab looking at prion trafficking by exosomes published today in JBC: Guo BB, Bellingham SA, Hill AF. Stimulating the release of exosomes increases the intercellular transfer of prions. J Biol Chem. 2016 Jan 14. pii: jbc.M115.684258. [Epub ahead of print]